Panola County is a county located in the U.S. state of Mississippi. As of the 2010 census, the population was 34,707. Its county seats are Sardis and Batesville. Panola is a Cherokee word which means cotton. The county is located just east of the Mississippi Delta and bisected by the Tallahatchie River flowing to the southwest, separating the two county seats.
Panola County was established February 9, 1836, and is one of the twelve large northern Mississippi counties created that year from the territory of the Chickasaw Cession of 1832.
According to the U.S. Census Bureau, the county has a total area of 705 square miles (1,830 km²), of which 685 square miles (1,770 km²) is land and 20 square miles (52 km²) (2.8%) is water.
As of the 2010 United States Census, there were 34,707 people residing in the county. 49.4% were White, 48.6% Black or African American, 0.2% Native American, 0.2% Asian, 0.6% of some other race and 0.9% of two or more races. 1.4% were Hispanic or Latino (of any race).
As of the census of 2000, there were 34,274 people, 12,232 households, and 9,014 families residing in the county. The population density was 50 people per square mile (19/km²). There were 13,736 housing units at an average density of 20 per square mile (8/km²). The racial makeup of the county was 50.48% White, 48.36% Black or African American, 0.16% Native American, 0.18% Asian, 0.01% Pacific Islander, 0.41% from other races, and 0.39% from two or more races. 1.12% of the population were Hispanic or Latino of any race.
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